In-hospital mortality among patients with proximal femur fractures infected with COVID-19.

The COVID-19 pandemic has significantly reduced the number of orthopedic surgeries world- wide. The main reason for this was an introduction of numerous restrictions in the field of mobility, which resulted in reduction of circumstances predisposing to injuries. This had a positive impact on the overall readiness of the health system to fight the pandemic, thanks to saving human and material resources that could be successfully allocated in order to fight a new, previously unknown threat. On the other hand, such aimed administration of the system was not indifferent in terms of care quality directed towards traumatized patients, often requiring immediate measures (risk of infection transmission). This study aims to evaluate in-hospital mortality in patients with COVID-19 operated on proximal femur fractures. An attempt was also made to determine predictors influencing mortality rate among patients operated over the analyzed period.

Risk Factors of 120-Day Mortality Among Hip Fractures With Concomitant COVID-19 Infection.

Background Hip fractures cause substantial morbidity and mortality worldwide, and the coronavirus disease 2019 (COVID-19) pandemic has only worsened the global burden. Increased 120-day mortality is well established in the literature among hip fractures with COVID-19. However, the risk factors associated with mortality have been poorly understood. We aimed to determine the risk factors associated with increased 120-day mortality among hip fractures with COVID-19. Methods Seventy patients with hip fractures with confirmed COVID-19 infection between March 2020 and December 2021 were included. Thirty-three patients who died within 120 days of admission were allotted to the non-survivor group and the rest 37 patients were allotted to the survivor group. Various parameters such as demographic variables, Nottingham Hip Fracture Score (NHFS), Charlson Comorbidity Index (CCI), American Society of Anesthesiologists (ASA), Abbreviated Mental Score Test (AMTS), National Early Warning Score (NEWS), fracture type, operation type, and delay in surgery were compared between the groups to determine the risk factors for increased mortality. Multivariate regression analysis was performed to know the independent association with increased mortality. Results A total of 33 patients died within 120 days giving the 120-day mortality rate of 47.1%. Baseline parameters such as ASA, AMTS on admission, NEWS on admission, and type of residence did not significantly affect mortality. The mean NHFS was significantly high in non-survivors (5.38 ± 1.52) compared to survivors (4.40 ± 1.75) (p < 0.001). Similarly, mean CCI was also significantly high in non-survivors (5.58 ± 1.74) compared to survivors (4.76 ± 2.29) (p < 0.001). A total of 70% (seven out of 10) of patients with delayed surgery of more than 36 hours from the admission died within 120 days of admission (p < 0.001). Mortality was significantly higher in patients who underwent internal fixation of fractures like a dynamic hip screw (DHS) or intramedullary (IM) nailing than in those who underwent hemiarthroplasty or total hip arthroplasty (THA). Post-operative parameters such as early mobilization and the multidisciplinary approach to review these patients made no difference to the mortality. Multivariate regression analysis of the parameters that made a significant difference in the mortality showed that delay in surgery and type of surgery (internal fixation) independently increased the mortality among these patients (p < 0.001). However, NHFS and CCI were not independently affecting the mortality among hip fractures with concomitant COVID-19. Conclusion The 120-day mortality rate among patients with hip fractures with concomitant COVID-19 was 47.1%. Delay in surgery of more than 36 hours and patients who underwent internal fixation were independent risk factors associated with increased mortality among these patients.

Traumatic Proximal Femoral Fractures during COVID-19 Pandemic in the US: An ACS NSQIP® Analysis.

In order to determine the impact of COVID-19 on the treatment and outcomes in patients with proximal femoral fracture's (PFF), we analyzed a national US sample. This is a retrospective review of American College of Surgery's (ACS) National Surgical Quality Improvement Program (NSQIP) for patients with proximal femoral fractures. A total of 26,830 and 26,300 patients sustaining PFF and undergoing surgical treatment were sampled during 2019 and 2020, respectively. On multivariable logistic regression, patients were less likely to have 'presence of non-healing wound' (p < 0.001), functional status 'independent' (p = 0.012), undergo surgical procedures of 'hemiarthroplasty'(p = 0.002) and 'ORIF IT, Peritroch, Subtroch with plates and screws' (p < 0.001) and to be 'alive at 30-days post-op' (p = 0.001) in 2020 as compared to 2019. Patients were more likely to have a case status 'emergent', 'loss of ≥10% body weight', discharge destination of 'home' (p < 0.001 for each) or 'leaving against medical advice' (p = 0.026), postoperative 'acute renal failure (ARF)' (p = 0.011), 'myocardial infarction (MI)' (p = 0.006), 'pulmonary embolism (PE)' (p = 0.047), and 'deep venous thrombosis (DVT)' (p = 0.049) in 2020 as compared to 2019. Patients sustaining PFF and undergoing surgical treatment during pandemic year 2020 differed significantly in preoperative characteristics and 30-day postoperative complications when compared to patients from the previous year.

Society for the Advancement of Patient Blood Management 2022 Scientific Abstracts

The proceedings contain 46 papers. The topics discussed include: anemia assessment with benchmarking of red blood cell transfusion risk in cardiac surgery;clinical outcomes and therapeutic strategies for gastrointestinal bleeding in patients who decline transfusion;effect of patient blood management program on outcomes of the elderly with femur fracture who underwent orthopedic surgery;effect of ultrafiltration during cardiopulmonary bypass on viscoelastic profiles in cardiac surgery: retrospective analysis;hemoglobin based oxygen carrier treatment and clinical outcomes in severe anemia when blood is not an option;hemoglobin, lactate dehydrogenase, and FACIT-fatigue normalization in pegcetacoplan-treated patients with paroxysmal nocturnal hemoglobinuria;implementing three key blood management measures during COVID-19 related inventory shortages;and managing preoperative anemia using a novel algorithm to determine the preoperative target hemoglobin.

Physiotherapy Rehabilitation to Recuperate a Patient From an Intertrochanteric Fracture: A Case Report.

Intertrochanteric fracture is a prevalent condition among older adults, and it is becoming more so as the population is aging. A 52-year-old man was reported to the hospital with symptoms of pain and swelling in the right hip since the morning. The patient reported a history of unexpected slips and falls in the morning. An X-ray was taken of both hips, and an intertrochanteric fracture was identified. After one month post-fracture, a dynamic hip screw (DHS) was used to perform open reduction internal fixation (ORIF). Early mobility, appropriate lower limb strength, pain reduction, and quality of life are all significant determinants. As evidenced by statistically significant improvements in exercise capacity and well-being, the intertrochanteric fracture rehabilitation program is beneficial. This case study represents a comprehensive rehabilitation program for people who have had post-fracture surgery.

Mortality in COVID-19 patients after proximal femur fracture surgery: a systematic review and meta-analysis.

BACKGROUND: COVID-19 infection first emerged in December 2019 in China and has since rapidly spread to become a worldwide pandemic. Orthopaedic surgery suffered a significant decline in the volume of surgical cases, while the orthopaedic trauma services maintained or increased the activity. Emergency operations for proximal femur fractures (PFF) in the elderly population assumed levels comparable to before the pandemic, with the 1-year mortality rate ranging from 14% to 36%. AIMS: To determine whether patients with PFF affected by COVID-19 have a higher risk of postoperative mortality through a systematic review and meta-analysis. METHODS: PubMed, Web of Science, Scopus and BMC were searched from January 2020 to January 2021 to identify original studies reporting the mortality in COVID-19 patients after PFF surgery. Study and participants' characteristics, mortality rate and odds ratio (OR) were extracted. Risk of bias assessment was carried, and visual inspection of the funnel plot was used to assess publication bias. A random-effects model for meta-analysis was adopted. RESULTS: Among 656 articles that came from the search query and hand-search, 10 articles were eligible after applying inclusion and exclusion criteria. Overall, the sum of the study participants was 1882, with 351 COVID-19 positive patients (18.7%) and a total number of 117 deaths, with an overall mortality rate of 33.3%. The mortality rate of COVID-19 positive patients varied from 14.8% to 60% and was higher than of those without COVID-19, with OR ranging from 2.424 to 72.00. The inverse variance method showed an OR = 3.652. All studies showed a statistically significant p-value. CONCLUSIONS: The postoperative mortality in hip fracture patients with concomitant COVID-19 was 3.65 times higher than the mortality in non-COVID patients. The currently available literature demonstrates that COVID-19 infection represents a substantial risk factor for postoperative mortality in the already susceptible hip fracture population.

Abstracts SECCA 2021

The proceedings contain 24 papers. The topics discussed include: applications of 3d models in pelvis and hip surgery;intraoperative fractures of the acetabulum in total hip arthroplasty;does depression influence postoperative total hip atroplasty?;are we meeting patient's expectations after hip preserving surgery?;hip fractures during the COVID-19 pandemic: characteristics, management and outcomes;digital preoperative planning in total hip arthroplasty: our experience;emphysematous osteomyelitis of the hip: a case report;how a tripolar system helps us in revision surgery hip;clinical and radiological risk factors for revision surgery in primary total hip replacement: a study on 4,013 total hip replacements from 2000 to 2020;and peri-prosthetic Vancouver B2 post operative femoral fractures. clinical, functional and radiographic outcomes in a case series.

EMS 2022

The proceedings contain 42 papers. The topics discussed include: adverse events from nitrate administration during right ventricular myocardial infarction: a systematic review and meta-analysis;family members screaming for help makes it very difficult to don PPE. a qualitative report on ambulance staff experiences of personal protective equipment (PPE) use and infection prevention and control (IPC) practices during the COVID-19 pandemic;resuscitation academy Germany - systemic improvements for better out-of-hospital cardiac arrest outcomes;nurse practitioners EMS (NP-EMS) performed ultrasound (US)-guided fascia iliaca compartment block (FIC-BLOCK) in patients with a suspected proximal femur fracture. preliminary data;developing a young persons advisory group (YPAG) to inform the design of a study to improve pre-hospital pain management for children and young people (CYP);and introduction of video triage of children with respiratory symptoms at a medical helpline.

Thirty-day mortality in patients with a proximal femur fracture during the COVID-19 pandemic in Biscay (Basque Country). / [Artículo traducido] Mortalidad a 30 días en pacientes con fractura de fémur proximal durante la pandemia COVID-19 en Vizcaya (País Vasco).

OBJECTIVES: Compare 30-day mortality rate following a proximal femur fracture (PFF) and SARS-CoV-2 infection versus a PFF and no SARS-CoV-2 infection. DESIGN: Retrospective comparative study. SETTING: Three university hospitals in Biscay province (Basque Country, Spain). PATIENTS: 77 patients over 65 years-old with PFF (AO 31-A and 31-B). INTERVENTION: Study conducted between 9 March and 15 April 2020. The COVID-19 group included only patients with SARS-CoV-2 infection, confirmed by a positive RT-PCR test. MAIN OUTCOME MEASUREMENTS: 30-Day mortality rate and risk factors for mortality. RESULTS: Of a total 77 patients, 10 were diagnosed with SARS-CoV-2 infection. Mean age was 85 years. Patients with SARS-CoV-2 infection had higher BMI (29.53 kg/m2) compared to patients without infection (24.09 kg/m2) (p = 0.001). No significant differences were found between both groups in terms of the Charlson Comorbidity Index, ASA score, use of oral anticoagulants or presence of cognitive impairment. Seven of the 10 patients in the COVID-19 group developed (viral) pneumonia, as compared to one single case (1/67) of (bacterial) pneumonia in the control group (p < 0.001). Thirty-days mortality was higher (p = 0.03) in COVID-19 patients (40%) than in those in the control group (11.9%). In the multivariate analysis, age ≥ 91 years-old, ASA class IV and BMI > 25 kg/m2 were significant predictors of 30-day mortality. All deaths in the COVID-19 group occurred while the patients were hospitalized. CONCLUSIONS: SARS-CoV-2 infection in patients with a PFF was seen to result in higher rates of early mortality, with COVID-19-related pneumonia being the leading direct cause of mortality. LEVEL OF EVIDENCE: Level III study.

A Completed Audit Cycle Examining Quality Improvement Pre and Post Introduction of Ed Multi-Disciplinary Simulation Based Medical Education Training on the Tallaght Hospital Hip Fracture Pathway

Introduction: The care of patients with hip fractures is a surrogate marker of trauma care. Irish hip Fracture Standard 1 involves patients with a hip fracture being admitted to an orthopaedic ward bed within 4 hours of attending the ED. We wanted to audit our current practice and introduce a quality improvement project to improve the timeliness and efficiency of care of our hip fracture patients compared with the gold standard IHFS 1. We introduced a 90-minute multidisciplinary simulation training programme on the hip fracture pathway to our ED in February 2021. All key stakeholders were represented;from Emergency Medicine, Orthopaedics, Nursing (EM and Orthopaedic), Radiology, Radiography, Porters (32 people overall). Because of Covid-19, the training was available in person and online via zoom. Methods: We performed a retrospective audit of patients presenting to TUH ED with a proximal third of femur fracture between 4th February and 31st March inclusive in 2020 and 2021, pre and post introduction of multidisciplinary simulation based medical education on the hip fracture pathway. Data was collected from the electronic record database (symphony). Results: 2020 n = 31;Average time to ward-8hrs 29 mins. 26% patients reached ward <4 hours. (8/31). 2021 n = 25;Average time to ward-5hrs 58 mins (32% reduction vs 2020). 72% patients reached ward <4 hours. (18/25) (46% increase vs 2020). Conclusion: Simulation based medical education is a successful intervention to improve compliance with our hip fracture pathway, time from presentation to transfer to an orthopaedic ward bed and achieve IHFS 1.

Improving early mobilisation following femoral fracture using a therapy led education programme

Keywords: Femoral fracture;Early mobilisation;Education Purpose: Early mobilisation following a femoral fracture is a key hip fracture metric and is associated with improved outcomes related to acute length of stay, morbidity and mortality. A local HipSprint audit found a disproportionate number of patients remain in bed if not seen by a Physiotherapist by post operation day 1 and the most common reasons for not being able to mobilise from bed with Physiotherapist were postural hypotension and pain. We planned to provide education, training and empowerment to the trauma ward healthcare assistants so they would be able to: (a) Successfully mobilise a proportion of “less complex” patients by POD 1 prior to physiotherapy assessment. This would allow more Physiotherapy time to be better utilised providing education, and specific rehabilitation to progress patients at an earlier stage of their journey. (b) identify when not appropriate to mobilise and wait for Physiotherapist to assess. (c) Identify issues preventing mobilisation by HCAs e.g. pain, hypotension and begin to modify these by: (i) Prompting the nurse that additional analgesia is needed (ii) Encourage patient to drink more fluid to improve BP These actions would increase the chance that the Physiotherapist would be able to mobilise the patient later that day. This was called the Out Of Bed Project (OOBP) and the aim was to increase the percentage of patients mobilised by post operation day 1. Methods: We provided a confidence questionnaire to all HCAs on our trauma ward to identify key areas to develop a competency checklist for education and training. A 2:1 training model was used with a physiotherapist providing a 1-hour face to face session to 2 HCAs to complete the competency checklist followed by observation and feedback when next mobilising a patient for the first time in order to be “signed off”. We used a model for improvement methodology to identify a system change for improving the out of bed rate for patients following femoral fracture surgery and using the NHFD to measure improvements in the 6-months following the project launch with data from the previous three years. A PDSA cycle was used to identify stakeholders, develop a training programme, roll out the project on one ward and measure improvements. Results: In 2018, 2019 and the first 6-months of 2020 the monthly average for patients mobilised from bed by post operation day 1 was 60%. Following the therapy led ward education programme this increased to 76.7%. Conclusion(s): • The number of patients mobilised from bed following surgery has increased noticeably, to 76.7% since the introduction of the OOBP. • This project highlights the benefit of therapy led education in improving early mobilisation for femoral fracture patients and having a positive influence in changing ward culture. • Considering the challenges of Covid-19 and the inclusion of ALL femoral fractures since April 2020 this is a great achievement considering this has been persistently around 60%. Impact: We plan to develop the OOBP to include awareness and education of delirium following surgery. We are now planning to implement this initiative to other ward/speciality areas in the Trust. Funding acknowledgements: This work was not funded.

Fracture in a Person with Spinal Cord Injury with Heterotopic Ossification due to Improper Exercise in Pandemic: A Case Report

Fractures following inappropriate exercises are rarely reported in Spinal Cord Injury (SCI) population. During pandemic physical inactivity and barriers to access to rehabilitation facility are conspicuous. Authors report a case of femur fracture following improper exercise and its interrelationship with Heterotopic Ossification (HO) and impact of pandemic. A 23-year-old male with American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade C tetraplegia presented with operated left femur shaft fracture following care-partner administered sudden improper exercise. X-ray of left hip and femur revealed HO around left hip joint and intramedullary nailing of shaft of femur. Routine rehabilitation protocol for SCI was followed especially focusing on safety home-exercise precaution program during pandemic time. To the best of our knowledge, this is the first case report of long bone fracture in a person with SCI following improper exercise which is influence by pandemic situation. Here, we described the causation of fracture in perspective of the vicious cycle of HO, improper exercise and pandemic impact. Further studies are required to find out appropriate precautionary guidelines regarding exercise during pandemic times for people with SCI.

Audit cycle examining quality improvement post emergency department multi-disciplinary simulation based medical education training on hip fracture care

Background: The care of patients with hip fractures is a surrogate marker of trauma care. Irish hip Fracture Standard 1 involves patients with a hip fracture being admitted to an orthopaedic ward bed within 4 hours of attending the ED. We wanted to audit our current practice and introduce a quality improvement project to improve the timeliness and efficiency of care of our hip fracture patients compared with the gold standard IHFS 1. We introduced a 90 minute multidisciplinary simulation training programme on the hip fracture pathway to our ED in February 2021. All key stakeholders were represented;from Emergency Medicine, Orthopaedics, Nursing (EM and Orthopaedic), Radiology, Radiography, Porters (32 people overall). Because of COVID-19, the training was available in person and online via Zoom. Methods: We performed a retrospective audit of patients presenting to TUH ED with a proximal third of femur fracture between 4th February and 31st March inclusive in 2020 and 2021, pre and post introduction of multidisciplinary simulation based medical education on the hip fracture pathway. Data was collected from the electronic record database (Symphony). We recorded the following data;Results: 2020 n=31. Average time to ward-8 hrs 29 mins. 26% patients reached ward <4 hours. (8/31). 2021 n=25. Average time to ward-5 hrs 58 mins (32% reduction vs 2020). 72% patients reached ward <4 hours. (18/25) (46% increase vs 2020). Conclusion: Simulation based medical education is a successful intervention to improve compliance with our hip fracture pathway, time from presentation to transfer to an orthopaedic ward bed and achieve IHFS 1.

Decrease in incidence of proximal femur fractures in the elderly population during the Covid-19 pandemic: a case-control study.

BACKGROUND: The World Health Organization classified Covid-19 as a pandemic during the first months of 2020 as lockdown measures were implemented globally to mitigate the increasing incidence of Covid-19-related morbidity and mortality. The purpose of this study was to evaluate the effect of national lockdown measures on proximal femur fracture epidemiology. Our hypothesis was that due to the prolonged period of stay-at-home orders, we would observe a decrease in the incidence of proximal femur fractures during the years 2020-21. METHODS: A retrospective case-control study of 2784 hip fractures admitted to the emergency department at one hospital between January 1, 2010, and March 31, 2021, was conducted. Cases were stratified weekly, and an analysis was conducted comparing cases occurring during government-imposed lockdown periods of 2020-21 to corresponding periods during 2010-2019. Furthermore, the trend of cases throughout the year of 2020 was observed. RESULTS: Of all proximal femur fracture cases included, 2522 occurred between 2010-2019 and 261 during the Covid-19 period. There was no significant difference in age (81.95 vs. 82.09; P = 0.78) or gender (P = 0.12). There was a total decrease of 21.64% in proximal femur fracture per week during the entirety of the Covid-19 pandemic period compared to the previous years (3.64 ± 1.99 vs. 4.76 ± 0.83; P = 0.001). During all three lockdown periods, there was a significant decrease in proximal femur fracture cases per week (3.55 ± 2.60 vs. 4.87 ± 0.95; P = 0.04), and the most pronounced decrease occurred during the third lockdown period (2.89 ± 1.96 vs. 5.23 ± 1.18; P = 0.01). CONCLUSION: We observed a total decrease in the number of proximal femur fractures occurring during the Covid-19 era compared to previous years and specifically a decrease of cases occurring during the government-imposed lockdown periods. The decrease in cases was more pronounced during the second and third lockdown periods.

Improving Secondary Bone Protection Prescription in Patients Admitted With a Femoral Neck Fracture.

Background The socioeconomic burden caused by fragility fractures is well recognised in today's ageing society, with hip fractures making a notable contribution. There is a significant national drive for secondary-prevention bone-protection prescription given the high morbidity and mortality rates of femoral neck fractures. A Specific, Measurable, Achievable, Relevant, Time-bound (SMART) aim was constructed to reach the gold standard in a level 2 trauma centre, utilising the Model for Improvement methodology. Methodology Baseline data were collected for 79 consecutive patients admitted with a neck of femur fracture. A total of 14% were managed with bone-protection plans. The root cause analysis identified three elements having a major impact on the prescription of secondary bone-protection medication: the lack of awareness, education, and a structured multidisciplinary team (MDT) approach. Appropriate plan-do-study-act cycles were implemented and change audited. Results Following cycles one and two, the mean percentage of patients managed with bone-protection plans increased from 14% to 44% and 76%, respectively. A statistical process control chart demonstrated positive change for each cycle, with p-values of <0.01 and <0.001, respectively. After our final cycle, 100% of patients suffering from a femoral neck fracture were being managed with appropriate bone-protection plans according to the Royal College of Physicians' national hip fracture database. We observed 100% sustainability two years later, despite the coronavirus disease 2019 pandemic service disruptions and redeployment of staff. Conclusions Departmental awareness and education played an important role in this quality improvement project. The ultimatum and sustainability intervention was 'responsibility charting' among the MDT: setting clear roles within the team to deliver better patient care.

The effect of COVID-19 positivity on inflammatory parameters and thirty day mortality rates in patients over sixty five years of age with surgically treated intertrochanteric fractures.

PURPOSE: To evaluate the effect of COVID-19 positivity on inflammatory parameters and 30-day mortality rates in patients over 65 years of age who were operated on for intertrochanteric femur fractures (IFF). METHODS: Eighty-seven patients (31 males, 56 females) who had a dynamic hip screw (DHS) or proximal femur nail (PFN) for the IFF between March 2020 and November 2020 were included in the study. The patients were divided into two groups as COVID-19 confirmed and probable positive (Group 1) and COVID-19 negative (Group 2). Time to surgery, operation duration, length of hospital stay, 30-day mortality, rates of the intensive care unit (ICU) referral, and inflammatory parameters such as haemoglobin, CRP, sedimentation, PCT, D-Dimer, and ferritin were evaluated. RESULTS: No significant difference was observed in terms of demographic data such as age, gender, comorbidity, and fracture type between the groups. Thirty-day mortality, ICU referral rate, blood transfusion rate, and hospitalization period were higher in Group 1 (p = 0.016, p = 0.012, p = 0.031, and p = 0.011, respectively). The inflammatory parameters were higher in Group 1 compared to Group 2 in the preoperative and postoperative periods (p < 0.05). CONCLUSION: COVID-19 positivity increases inflammatory parameters (as expected) and increases the 30-day mortality and ICU requirement in patients with surgically treated IFF.

Cessation of Pulsed Lavage During the SARS-CoV-2 Pandemic: The Effect on Hip Hemiarthroplasty Cement Mantles.

Background With the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, we were issued with guidance to minimize aerosol-generating procedures and discontinued the use of pulsed lavage for hip hemiarthroplasty. Instead, we used a bladder syringe to wash the femoral canal. The aim of this study was to assess whether this change in practice had a detrimental effect on the quality of the bone cement mantles in patients undergoing cemented hip hemiarthroplasty. Methodology We performed a retrospective review of all patients treated at a tertiary teaching hospital in the United Kingdom (Addenbrookes, Cambridge University Hospitals) presenting with a neck of femur fracture requiring a hemiarthroplasty between October 2019 and June 2020. We retrospectively assessed 100 post-operative radiographs for patients who had received hip hemiarthroplasty following neck of femur fragility fracture (50 before the service change and 50 after). The Barrack classification was used to assess the quality of the bone cement mantle. Results Pre-SARS-CoV-2, 30% of hemiarthroplasties were deemed as being "at risk" of aseptic loosening. During SARS-CoV-2, 64% of hips were deemed as being "at risk." This represents a statistically significant absolute increase of 34% (P < 0.05, the P value is 0.000645). Both clinicians agreed on the classification of hips "at risk" or "not at risk" (i.e., grades C/D and A/B, respectively) in 85% of the cases. Cohen's kappa coefficient was calculated as 0.68, indicating substantial agreement. Conclusions Following our experience of this forced service change, we would discourage abandoning the use of pulsed lavage in future pandemics. We have demonstrated an association between abandoning pulsed lavage and detrimental effects on the procedural quality for hip hemiarthroplasty. Patients treated over this time period will be closely monitored for operative complications. As this was the only equipment change made for this procedure, we have demonstrated its detrimental effect on the procedural quality. Should pulsed lavage be discontinued, patients may need to be counseled for higher risk of early failure and revision surgery and may require long-term radiographic follow-up. In SARS-CoV-2-positive patients, Surgeons should carefully consider the risks and benefits of using pulsed lavage in accordance with the personal protective equipment they have available and the consequential impact on the bone cement mantle quality.

The Impact of COVID-19 on Neck of Femur Fracture Care: A Major Trauma Centre Experience, United Kingdom.

BACKGROUND: The aim of this study was to investigate the impact of the COVID-19 pandemic on the management and outcome of patients with neck of femur fractures. METHODS: Data was collected for 96 patients with neck of femur fractures who presented to the emergency department between March 1, 2020 and May 15, 2020. This data set included information about their COVID-19 status. Parameters including inpatient complications, hospital quality measures, mortality rates, and training opportunities were compared between the COVID-19 positive and COVID-19 negative groups. Furthermore, our current cohort of patients were compared against a historical control group of 95 patients who presented with neck of femur fractures before the COVID-19 pandemic. RESULTS: Seven (7.3%) patients were confirmed COVID positive by RT-PCR testing. The COVID positive cohort, when compared to the COVID negative cohort, had higher rates of postoperative complications (71.4% vs 25.9%), increased length of stay (30.3 days vs 12 days) and quicker time to surgery (0.7 days vs 1.3 days).The 2020 cohort compared to the 2019 cohort, had an increased 30-day mortality rate (13.5% vs 4.2%), increased number of delayed cases (25% vs 11.8%) as well as reduced training opportunities for Orthopaedic trainees to perform the surgery (51.6% vs 22.8%). CONCLUSION: COVID-19 has had a profound impact on the care and outcome of neck of femur fracture patients during the pandemic with an increase in 30-day mortality rate. There were profound adverse effects on patient management pathways and outcomes while also affecting training opportunities.

Thirty-day mortality in patients with a proximal femur fracture during the COVID-19 pandemic in Biscay (Basque Country).

Objectives: Compare 30-day mortality rate following a proximal femur fracture (PFF) and SARS-CoV-2 infection versus a PFF and no SARS-CoV-2 infection. Design: Retrospective comparative study. Setting: Three university hospitals in Biscay province (Basque Country, Spain). Patients: 77 patients over 65 years-old with PFF (AO 31-A and 31-B). Intervention: Study conducted between 9 March and 15 April 2020. The COVID-19 group included only patients with SARS-CoV-2 infection, confirmed by a positive RT-PCR test. Main outcome measurements: 30-day mortality rate and risk factors for mortality. Results: Of a total 77 patients, 10 were diagnosed with SARS CoV-2 infection. Mean age was 85 years. Patients with SARS-Cov-2 infection had higher BMI (29.53 kg/m2) compared to patients without infection (24.09 kg/m2) (p = 0.001). No significant differences were found between both groups in terms of the Charlson Comorbidity Index, ASA score, use of oral anticoagulants or presence of cognitive impairment. Seven of the 10 patients in the COVID-19 group developed (viral) pneumonia, as compared to one single case (1/67) of (bacterial) pneumonia in the control group (p < 0.001). Thirty-days mortality was higher (p = 0.03) in COVID-19 patients (40%) than in those in the control group (11.9%). In the multivariate analysis, age ≥91 years-old, ASA class IV and BMI >25 kg/m2 were significant predictors of 30-day mortality. All deaths in the COVID-19 group occurred while the patients were hospitalized. Conclusions: SARS CoV-2 infection in patients with a PFF was seen to result in higher rates of early mortality, with COVID-19-related pneumonia being the leading direct cause of mortality.

Objetivos: Comparar la tasa de mortalidad a 30 días en los pacientes con fractura de fémur proximal (FFP) y coinfección por SARS-CoV-2 frente a FFP sin coinfección. Diseño: Estudio retrospectivo comparativo. Escenario: Tres hospitales universitarios en Vizcaya (País Vasco, España). Pacientes: Setenta y siete pacientes mayores de 65 años con FFP (AO 31-A y 31-B). Intervención: Entre el 9 de marzo y el 15 de abril de 2020. El grupo COVID-19 incluía pacientes con infección confirmada mediante el test PCR-RT. Medidas de resultados principales: Tasa de mortalidad a 30 días y factores de riesgo de mortalidad. Resultados: Diez de los 77 pacientes presentaron coinfección por SARS-CoV-2. La edad media fue de 85 años. Los pacientes infectados presentaban un IMC mayor (29,53 kg/m2) frente a los no infectados (24,09 kg/m2) (p = 0,001). No hubo diferencias significativas en el índice de comorbilidad de Charlson, la puntuación ASA, el uso de anticoagulantes o el deterioro cognitivo. Siete pacientes del grupo COVID-19 (7/10) desarrollaron neumonía (vírica), frente a un solo caso (1/67) de neumonía (bacteriana) en el grupo control (p < 0,001). La mortalidad a 30 días fue mayor (p = 0,03) en los pacientes con COVID-19 (40%) que en el grupo control (11,9%). La edad ≥ 91 años, la clase IV ASA y el IMC > 25 kg/m2 fueron predictores significativos de mortalidad a 30 días. Todas las muertes en el grupo COVID-19 ocurrieron intrahospitalariamente. Conclusiones: La infección por SARS-CoV-2 en pacientes con PFF resultó en tasas más altas de mortalidad temprana, siendo la neumonía por COVID-19 la principal causa directa de mortalidad.Nivel de evidencia: Estudio nivel III.

Thirty-day mortality and reliability of Nottingham Hip Fracture Score in patients with COVID19 infection.

In March 2020 Coronavisus-19 pandemic led to significant changes in operations in healthcare in the United Kingdom with national lockdown measures imposed to help protect the vulnerable and prevent transmission. Those deemed vulnerable fall into the cohort of patients at risk of fragility fractures such as fracture neck of femur (NOF). British Orthopaedic Association released guidelines advising that NOF fractures should continue to be treated urgently. AIM: Our unit aimed to identify changes in NOF caseload during the national lockdown and identify if Nottingham Hip Fracture Scores (NHFS) were reliable at predicting 30-day mortality in COVID-19 positive patients. METHODS: A retrospective observational study identifying NOF admissions over a 6-week period in 2020 during lockdown period, where demographics, NHFS, and 30-day mortality rates were compared against the same period in 2019. RESULTS: There was a reduction in NOF admissions by 17.8% (55 vs 67). No significant difference in patient demographics between groups. 30-day mortality rates were not significantly increased in 2020 compared with 2019. COVID-19 positive patients had significantly increased 30-day mortality rates (54%, p = 0.001) compared to COVID-19 negative (9.1%, p = 0.395) and 2019 (6%). DISCUSSION: NHFS was not reliable as a predictor for 30-day mortality in COVID-19 positive patients. Our unit reports increased mortality rates in NOF patients with covid-19 infection. This adds to the building evidence that COVID-19 is an independent predictor for mortality in NOF patients irrespective of NHFS. This should be communicated to patients who are admitted to hospital with NOF and units should continue with efforts to prevent hospital acquired COVID-19 infection.